Info Petani - Proceedings of Temu Ilmiah VIII, 1999: 269
Pub. ISSN : 0918-7685
Pudjiatmoko
National Veterinary Drug Assay Laboratory , Gunungsindur, Bogor 162340
Nine 12-week-old specific-pathogen-free (SPF) cats were randomly divided into three groups. Groups A and B were vaccinated with an experimental vaccine derived from the Fe/145 strain of feline Chlamydia psittaci. Cats of group A were injected intramuscularly with vaccine containing 105.5ELD50 of Chlamydia and those of the group B were vaccinated with 104.5ELD50 of Chlamydia. Cats of group C were injected with suspension of sucrose-phosphate-glutamic acid and adjuvant as control. Vaccinations were performed twice. The second vaccination was done on 3 weeks post first vaccination. One week post second vaccination, cats were challenged intraocular with live feline C. psittaci B166 strain. Two cats of group A showed clinical signs of Chlamydiosis. All cats of the groups B and C showed the clinical signs. IgG antibody titer was determined by using microimmunofluorescence test. On the day of challenge, IgG antibody titers of cats of group A were 1:128 to 1:256, while those of group B were 1:64 to 1:128. The results indicate that cats should be injected with the vaccine containing Chlamydia more than 105.5ELD50 to give good protection against infection of Chlamydia.
dan sekian itulah artikel Respon Dosis Vaksin Inaktif Chlamydosis terimakasih ^_^
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